Resident Population in Lee County, SC was 15.96700 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Lee County, SC reached a record high of 20.37400 in January of 1998 and a record low of 15.96700 in January of 2023. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Lee County, SC - last updated from the United States Federal Reserve on May of 2024.