Resident Population in Holmes County, MS was 15.77700 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Holmes County, MS reached a record high of 24.10000 in January of 1971 and a record low of 15.77700 in January of 2023. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Holmes County, MS - last updated from the United States Federal Reserve on May of 2024.