Resident Population in Hampden County, MA was 460.29100 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Hampden County, MA reached a record high of 469.56100 in January of 2014 and a record low of 440.46700 in January of 1983. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Hampden County, MA - last updated from the United States Federal Reserve on May of 2024.